Jeremiyah Love suited up for the Cardinals' Week 1 game against the Chargers. He entered the day as a game-time decision due to an ankle issue. The Cardinals cleared him for his debut. Love was dressed and available from the start.

On his first professional possession, Love scored his first professional touchdown. He followed with an 18-yard run. The Cardinals used him in the season opener. His first score was part of a series that put the Cardinals on the board. Love proved his worth on the field.